Although oncogenic activation of tumour metabolism renders cancer cells possibly vulnerable to inhibition of different metabolic pathways, these pathways are also utilized by immune cells25, especially on receptor stimulation, including T mobile receptor (TCR) engagement along with CD28 activation.
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ATL suppresses the translocation of NF-κB p65/p50 and p300 as well as the binding of such proteins for the COX-2 promoter. a: Right after 48 h of ATL tre